Tag Archives: Tech

Florida’s War With Invasive Pythons Has a New Twist

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WIRED

It may not be possible to eradicate the state’s tens of thousands of Burmese pythons. But the local wildlife is biting back—and humans wielding new tech can help.

WHILE DRIVING IN the swamplands some 40 miles west of Miami, Mike Kirkland noticed a log lying in the road ahead, so he and his colleague stepped out of their white GMC work truck. This was no log. “As we got closer, we realized it was a python,” he says. “It was so big, it looked like a fallen tree.” Kirkland asked the colleague to hang back, then crept to within five feet of the predator as it basked on the warm pavement.

“She saw me,” he says. “I’m 5’11”. And she picked herself up and practically looked me in the eye.” The snake’s sheer size gave him pause—but not for long. She stretched open her mouth, revealing dozens of curved teeth as sharp as daggers, then launched her head at Kirkland. He dodged a couple of strikes before spotting an opening to grab the snake’s head. The nonvenomous 17-foot constrictor then tried to wrap herself around the sweating Kirkland, who slipped through coil after coil. About 20 minutes later, the exhausted snake gave in, and Kirkland euthanized the animal.

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A Hair Loss Study Raises New Questions About Aging Cells

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WIRED

A protein secreted by seemingly dormant cells in skin moles causes hair to grow again. That’s a big—and potentially useful—surprise.

MAKSIM PLIKUS loves talking about hair. The cell biologist from the University of California, Irvine rattles off obscure facts: Sloth hair has a green tinge thanks to symbiotic algae; African crested rats evolved hollow hairs, which they slather with a pasty bark-derived toxin to defend themselves; his last name comes from a Latvian word for “bald.” Growing up in Eastern Europe (he’s neither Latvian nor bald, despite his name), Plikus aspired to do biomedical research. He joined a lab that had him dissecting rat whiskers under a microscope. It was hard, and his hands would shake. But eventually he got the hang of it. “I started to appreciate just the beauty of the follicle,” he says.

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This Artificial Muscle Moves Stuff on Its Own

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WIRED

Actuators inspired by cucumber plants could make robots move more naturally in response to their environments, or be used for devices in inhospitable places.

IN THE PRODUCE section of a grocery store, the cucumber is mundane. But in the nursery section of a hardware store, says Shazed Aziz, the cucumber plant is a marvel.

A couple of years ago, Aziz strode through Bunnings Warehouse, an Australian hardware chain, making a beeline for a particular cucumber plant. The day before, he had noticed its peculiar tendrils—thin stems that jut out from the plant in coils of various sizes and that cucumber vines use to reach toward surfaces and pull themselves up to access more sunlight. On his first visit, those helix-like curls were long and loose. “When I returned to the store the next day, they were contracted,” says Aziz, a materials engineering postdoc at the University of Queensland.

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For AI to Know What Something Is, It Must Know What Something Isn’t

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Quanta Magazine

Today’s language models are more sophisticated than ever, but challenges with negation persist.

Nora Kassner suspected her computer wasn’t as smart as people thought. In October 2018, Google released a language model algorithm called BERT, which Kassner, a researcher in the same field, quickly loaded on her laptop. It was Google’s first language model that was self-taught on a massive volume of online data. Like her peers, Kassner was impressed that BERT could complete users’ sentences and answer simple questions. It seemed as if the large language model (LLM) could read text like a human (or better).

But Kassner, at the time a graduate student at Ludwig Maximilian University of Munich, remained skeptical. She felt LLMs should understand what their answers mean — and what they don’t mean. It’s one thing to know that a bird can fly. “A model should automatically also know that the negated statement — ‘a bird cannot fly’ — is false,” she said. But when she and her adviser, Hinrich Schütze, tested BERT and two other LLMs in 2019, they found that the models behaved as if words like “not” were invisible.

Read the full story in Quanta Magazine

Everyone Was Wrong About Reverse Osmosis—Until Now

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WIRED

A new paper showing how water actually travels through a plastic membrane could make desalination more efficient. That’s good news for a thirsty world.

MENACHEM ELIMELECH NEVER made peace with reverse osmosis. Elimelech, who founded Yale’s environmental engineering program, is something of a rock star among those who develop filtration systems that turn seawater or wastewater into clean drinking water. And reverse osmosis is a rock star among filter technologies: It has dominated how the world desalinates seawater for about a quarter of a century. Yet nobody really knew how it worked. And Elimelech hated that.

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Fighting Climate Change One Meal at a Time

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CHEMMATTERS

Beth Zotter can talk about anything. The problems she encounters as chief executive officer (CEO) of a food company named Umaro are very specific. But the main focus is algae—which Zotter’s Umaro Foods claims is the future of abundant, sustainable protein—and its mission is to save our planet from climate calamity.

Read the full story in ChemMatters April Issue

From Pond Scum to Product: The Chemistry of Algae

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CHEMMATTERS

The first time Beth Zotter tried her company’s bacon, it tasted bitter, and powdery. “Most protein concentrates don’t taste very well,” says Zotter, cofounder and chief executive officer of Umaro Foods. Umaro was attempting to re-create crispy, savory bacon out of seaweed.

Why bacon? “It’s America’s favorite food,” said co-founder Amanda Stiles on an episode of the TV show, “Shark Tank,” where the two raised funds for Umaro. “It’s the holy grail of plant-based meat. Sizzling, salty, delicious.” But the real magic of Umaro’s pitch was not the bacon. It was the algae.

Read the full story in ChemMatters April Issue

This Lab-Grown Skin Could Revolutionize Transplants

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WIRED

A new kind of “edgeless” engineered tissue can fit any irregular shape, paving the way for hand and face grafts that look and move better.

ALBERTO PAPPALARDO WAS nervous the morning before the transplant. He’d spent the previous month nurturing a cluster of skin cells until they reached their final form: a pinkish-white tissue in the shape of a mouse’s hindlimb that could be slipped onto the animal like a pant leg. If all went according to plan, the mouse’s surrounding skin would accept the lab-grown stuff as its own.

In the end, it took less than 30 seconds to position the new skin, and under 10 minutes to complete the whole procedure. “It was a perfect fit,” recalls Pappalardo, a medical doctor and postdoc focusing on dermatology and tissue engineering at Columbia University Medical Center. That’s a big deal, because it could help solve a persistent challenge in treating burns and other large wounds: how to cover irregular shapes with real, functional skin.

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This Fake Skin Fools Mosquitoes With Real Blood

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WIRED

Research on new repellents and the viruses these insects carry relies on lab animals and human volunteers. What if there was a better option?

THE WORLD’S DEADLIEST animal is a picky eater. Because they transmit viral diseases like Zika and chikungunya, and the parasites that cause malaria, mosquitoes like blood-sucking Aedes aegypti are responsible for over 700,000 deaths worldwide every year.

But in Omid Veiseh’s lab at Rice University, his team of bioengineers was struggling to get mosquitoes to eat. Typically, researchers study mosquitoe feeding by letting them bite live animals—lab mice, or grad students and postdocs who offer up their arms for science. That’s not ideal, because lab animals can be expensive and impractical to work with, and their use can raise ethical issues. Student arms don’t scale well for large tests.

In collaboration with entomologists from Tulane University, the Rice team wanted to develop a way of studying mosquito behavior without the challenges of experimenting on large numbers of animals. Their solution was something totally different: real blood encased in a lifeless hydrogel. “It feels like jello,” Veiseh says. “The mosquitoes have to bite through the jello to get to the blood.” 

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