Tag Archives: Sequencer

What we learn in the footsteps of wolves

Sequencer

Up close and personal with nature’s notoriously elusive carnivore.

In the summer of 1986, biologist L. David Mech crept over a hill on an island 500 miles from the North Pole and spotted a pack of white Arctic wolves. He’d spent days clambering over rocks and hiking across treeless ridges under 24-hour-daylight searching for a den. Few if any scientists had ever studied wolves at their dens. Mech had devoted nearly three decades to wolves, but rarely eavesdropped from the ground and never at a den. Now, 200 meters from his mattress, he counted one, two, three, four, five, six. Six five-week-old pups, along with seven adults, all unfazed by him and his ATV.

“It was the highlight of my life,” Mech later wrote in a National Geographic magazine. “After twenty-eight years, I had finally scored the Big One.” This marked the beginning of a renaissance in wolf biology that continues to this day; a renaissance that’s crept out of the Arctic and into wild and urban areas around the world.

Wolves are feared and revered from Norse and Roman mythology to Indigenous American tradition. In modern politics, they fracture public opinion over questions like What does it mean to conserve the wilderness? and at what cost to human lifestyles should we be protecting carnivores?

Wolves are elusive. Their internal and social lives are difficult to pin down. And our efforts to control them—even understand them—continuously turn up surprises.

Two recent books offer a rare lens into the lives of wolves. The Ellesmere Wolves, written by Mech and published in March, unfurls decades of observations of the world’s most tame wild wolf populations on the Canadian island of Ellesmere. Lone Wolf, from author Adam Weymouth, published in June, retraces the steps of Slavc, a wolf who famously journeyed across Europe alone in 2011 and 2012.

The contexts differ: Weymouth is a journalist following GPS data through beech forests, alpine prairies, and populated villages, discovering the grim political consequences of wolves’ success repopulating across Europe. Mech is a veteran field biologist documenting the world’s most remote Arctic wolves. Mech lived in close contact with wild wolves. He observed unprecedented behaviors around their dens like ambushing prey, and adults hugging chest-to-chest.

Yet, common themes emerge. Weymouth confronts the romantic ideal of a “lone wolf” who embarks on fiercely independent journeys. Mech, in his writings, confronts a wolf phenomenon that has transcended science into human culture—the alpha wolf.

“I think it’s really crucial to kind of tell these animal stories,” Weymouth told me. “But I do think those stories are really hard for people to connect to.”

Read the full story in Sequencer Magazine

The covert project to (finally) measure hellish subway heat

SEQUENCER MAG

Meet Jack Klein, the guy who stealthily collects data about New York’s hottest days underground.

At 181st street in New York’s Washington Heights neighborhood, an August heat wave broils the asphalt, concrete, and any inch of skin exposed to the sun. Shade offers some relief, with one major exception: the underground. Washington Heights resides several hundred feet above lower Manhattan, so its subway stops are buried deeper underground. “People tell me, you’ve gotta go to the elevator inside 181stit’s an inferno,” said Jack Klein, founder of NewYorkLab, a guerilla project to study environmental conditions at subway stations.

Read the full story at Sequencer Magazine

Nobody is making chocolate like this

Sequencer

What happens when you turn cacao into a microbiology experiment? Some damn good chocolate.

To say you “like chocolate” means almost nothing. There are people for whom chocolate means the rich soup of microwaved Ben & Jerry’s Phish Food; some gravitate to the syrupy bite of Hershey’s and others refuse to call Hershey’s “real” chocolate; there are the Lindt Lovers, Ferrero Rocher Freaks, and organic-bean-to-bar-fair-trade fans and stans. And then there’s Seamus Blackley, a physicist by training who didn’t think much about chocolate until he and mechanical engineer Asher Sefami began growing cacao trees in a secret lab just east of Los Angeles.

Read the full story in Sequencer

I tried to train my color vision. Here’s what happened.

Sequencer

When I gamified my color blindness, I stumbled into the limits and latitudes of neuroplasticity.

One afternoon during my PhD, I took a break from lab work to snack on a banana. I grabbed a seat in the office, slid off my headphones, and peeled open my treat. Just as I bit in, I noticed a labmate staring at me.

“Max,” she told me, holding back some laughter. “That banana is a 4.”

I instantly knew what she meant because I’d made this mistake before. The banana was days from being ripe, and I had misjudged the color. A laughably green banana.

Even before I knew that I had mild deuteranomaly (so-called red-green colorblindness), I struggled with cryptic color schemes on spreadsheets and graphs. Whether in spite or because of this, color theory fascinated me. I had neurological, practical, and philosophical questions. Why do we call the retina’s longest wavelength cone “red” when it actually best absorbs yellow-green light? Why does mixing paint obey different rules than mixing light? If I could see through your eyes, would your mental images match mine — does your blue match my blue? And I had questions that blended all three, like what the hell is brown???

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The drugs of the future are in the animals of the past

SEQUENCER

The genomes of extinct creatures like mammoths and giant sloths code for natural antibiotics we’ve never seen. So, now what?

César de la Fuente’s lab has a knack for finding antibiotics in usual places. He doesn’t trudge through swamps or remote forests like a pharmacological Indiana Jones. His lab instead combs through genetic data collected from creatures across all time.  

In just the last few years, they’ve documented unreported antimicrobial compounds hidden in the genomes of Neanderthals, the world’s microbes, and within ourselves. Now, their latest feat carries the torch thanks to a brand new machine learning algorithm they call APEX: antibiotic peptide de-extinction. 

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